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Preventing Diabetes Complications 

 

Preventing diabetes complications
Diabetes can affect many parts of the body and can lead to serious complications such as blindness, kidney damage,
and lower-limb amputations. Working together, people with diabetes and their health care providers can reduce the
occurrence of these and other diabetes complications by controlling the levels of blood glucose, blood pressure, and
blood lipids, and by receiving other preventive care practices in a timely manner.
Glucose control
Studies in the United States and abroad have found that improved glycemic control benefits people with either type
1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results (e.g., from 8.0% to 7.0%)
reduces the risk of microvascular complications (eye, kidney, and nerve diseases) by 40%.
Blood pressure control
Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with
diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by
approximately 33%.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to
diabetes is reduced by 12%.
Control of blood lipids
Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce
cardiovascular complications by 20% to 50%.
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, premature mortality)
These data are based on a study by the Lewin Group, Inc., for the American Diabetes Association and are 2002 estimates of both the
direct (cost of medical care and services) and indirect costs (costs of short-term and permanent disability and of premature death)
attributable to diabetes. This study used a specific cost-of-disease methodology to estimate the health care costs due to diabetes.

 
Preventing diabetes complications
Diabetes can affect many parts of the body and can lead to serious complications such as blindness, kidney damage,
and lower-limb amputations. Working together, people with diabetes and their health care providers can reduce the
occurrence of these and other diabetes complications by controlling the levels of blood glucose, blood pressure, and
blood lipids, and by receiving other preventive care practices in a timely manner.
Glucose control
Studies in the United States and abroad have found that improved glycemic control benefits people with either type
1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results (e.g., from 8.0% to 7.0%)
reduces the risk of microvascular complications (eye, kidney, and nerve diseases) by 40%.
Blood pressure control
Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with
diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by
approximately 33%.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to
diabetes is reduced by 12%.
Control of blood lipids
Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce
cardiovascular complications by 20% to 50%.
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, premature mortality)
These data are based on a study by the Lewin Group, Inc., for the American Diabetes Association and are 2002 estimates of both the
direct (cost of medical care and services) and indirect costs (costs of short-term and permanent disability and of premature death)
attributable to diabetes. This study used a specific cost-of-disease methodology to estimate the health care costs due to diabetes.

 
Preventing diabetes complications
Diabetes can affect many parts of the body and can lead to serious complications such as blindness, kidney damage,
and lower-limb amputations. Working together, people with diabetes and their health care providers can reduce the
occurrence of these and other diabetes complications by controlling the levels of blood glucose, blood pressure, and
blood lipids, and by receiving other preventive care practices in a timely manner.
Glucose control
Studies in the United States and abroad have found that improved glycemic control benefits people with either type
1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results (e.g., from 8.0% to 7.0%)
reduces the risk of microvascular complications (eye, kidney, and nerve diseases) by 40%.
Blood pressure control
Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with
diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by
approximately 33%.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to
diabetes is reduced by 12%.
Control of blood lipids
Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce
cardiovascular complications by 20% to 50%.
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, premature mortality)
These data are based on a study by the Lewin Group, Inc., for the American Diabetes Association and are 2002 estimates of both the
direct (cost of medical care and services) and indirect costs (costs of short-term and permanent disability and of premature death)
attributable to diabetes. This study used a specific cost-of-disease methodology to estimate the health care costs due to diabetes.
Acknowledgments
The following organizations collaborated in compiling the information for this fact sheet:
Agency for Healthcare Research and Quality
American Association of Diabetes Educators
American Diabetes Association
Centers for Disease Control and Prevention
Centers for Medicare and Medicaid Services
Department of Veterans Affairs
Health Resources and Services Administration
Indian Health Service
Juvenile Diabetes Research Foundation International
National Diabetes Education Program, a joint program of NIH and CDC
National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health
U.S. Department of Health and Human Services, Office of Minority Health
Note
This publication is not subject to copyright restrictions; please duplicate and distribute copies as desired.
Citation
Centers for Disease Control and Prevention. National diabetes fact sheet: general information and national
estimates on diabetes in the United States, 2005. Atlanta, GA: U.S. Department of Health and Human Services,
Centers for Disease Control and Prevention, 2005.
CDC Division of Diabetes Translation Public Inquiries/Publications
Phone toll free: 1-877-CDC-DIAB (877-232-3422)
Fax: 1-301-562-1050
E-mail: diabetes@cdc.gov
Mail: P.O. Box 8728, Silver Spring, MD 20910
Diabetes Glossary
Blood glucose
A1c blood
test
is the main sugar found in the blood and the body s main source of energy. The
is used to measure a person s average blood sugar level over the past 2 to 3 months.
Blood pressure is the force of blood on the inside walls of blood vessels, measured by analyzing both the
systolic blood pressure, the pressure when the heart pushes blood out into the arteries, and the diastolic
blood pressure, when the heart is at rest.
Blood lipid is a term for fat in the blood stream, and is measured with a lipid profile blood test. The lipid
profile test measures total cholesterol, the fat produced by the liver and found in some foods,
triglycerides, the storage form of fat in the body, HDL cholesterol, fat that takes extra cholesterol from
the blood to the liver for removal, and LDL cholesterol, fat that takes excess cholesterol around the body
to where it s needed, but excess ultimately rests on the inside of artery walls.
Diabetic ketoacidosis is a condition in which very high blood sugar levels along with a very low level of
insulin result in a dangerous accumulation of ketones -- substances produced when the body breaks down
fat for energy -- in the blood and urine. Hyperosmolar nonketotic syndrome is another condition in
which one s blood sugar levels become very high and necessary ketones are not present in the blood or
urine. Coma or death can result if both of these conditions are not treated.
Insulin is a hormone that is needed to convert sugar, starches, and other food into energy needed for daily
life.
Metformin is a medicine pill used to treat type 2 diabetes because it lowers blood sugar levels by reducing
the amount of sugar produced by the liver and helping the body respond better to insulin.
Maturity-onset diabetes of the young is a kind of type 2 diabetes that accounts for 1 to 5 percent of
people with diabetes and is a result of a defect in a single gene.
Non-traumatic lower-limb amputation is a procedure to remove through surgery damaged feet or legs,
where the injury was not caused by trauma (e.g., the injury was not caused by a car accident).
Diabetic retinopathy is diabetic eye disease that results from damage to the small blood vessels in the
retina, the back part of the eye that contains the cells that respond to light. It may lead to loss of eyesight.
Laser therapy, one possible treatment option, uses a strong beam of light to seal the leaking blood vessels
in the eye.
End-stage renal disease is kidney failure requiring dialysis or a transplant to survive.
Glucose intolerance is a condition in which the body has blood sugar levels higher than normal, but not
high enough to classify as diabetes. It is diagnosed using an oral glucose tolerance test which requires a
fasting period of 8 to 12 hours and the blood sugar is measured both fasting and 2 hours after drinking a
high-sugar drink.
* Links to non-Federal organizations are provided solely as a service to our users. Links do not constitute an
endorsement of any organization by CDC or the Federal Government, and none should be inferred. The CDC is
not responsible for the content of the individual organization Webpages found at this link.
Diabetes can affect many parts of the body and can lead to serious complications such as blindness, kidney damage,
and lower-limb amputations. Working together, people with diabetes and their health care providers can reduce the
occurrence of these and other diabetes complications by controlling the levels of blood glucose, blood pressure, and
blood lipids, and by receiving other preventive care practices in a timely manner.
Glucose control
Studies in the United States and abroad have found that improved glycemic control benefits people with either type
1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results (e.g., from 8.0% to 7.0%)
reduces the risk of microvascular complications (eye, kidney, and nerve diseases) by 40%.
Blood pressure control
Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with
diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by
approximately 33%.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to
diabetes is reduced by 12%.
Control of blood lipids
Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce
cardiovascular complications by 20% to 50%.
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, premature mortality
Diabetes can affect many parts of the body and can lead to serious complications such as blindness, kidney damage,
and lower-limb amputations. Working together, people with diabetes and their health care providers can reduce the
occurrence of these and other diabetes complications by controlling the levels of blood glucose, blood pressure, and
blood lipids, and by receiving other preventive care practices in a timely manner.
Glucose control
Studies in the United States and abroad have found that improved glycemic control benefits people with either type
1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results (e.g., from 8.0% to 7.0%)
reduces the risk of microvascular complications (eye, kidney, and nerve diseases) by 40%.
Blood pressure control
Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with
diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by
approximately 33%.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to
diabetes is reduced by 12%.
Control of blood lipids
Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce
cardiovascular complications by 20% to 50%.
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, premature mortality
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, prematu
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, prematu
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, prematu
Preventive care practices for eyes, kidneys, and feet
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss
by an estimated 50% to 60%.
Comprehensive foot care programs can reduce amputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in
kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are
more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
Estimated diabetes costs in the United States in 2002
Total (direct and indirect): $132 billion
Direct medical costs: $92 billion
Indirect costs: $40 billion (disability, work loss, prematu

Diabetes can affect many parts of the body and can lead to serious complications such as blindness, kidney damage, and lower-limb amputations. Working together, people with diabetes and their health care providers can reduce the occurrence of these and other diabetes complications by controlling the levels of blood glucose, blood pressure, and blood lipids, and by receiving other preventive care practices in a timely manner.

Glucose Control

Studies in the United States and abroad have found that improved glycemic control benefits people with either type 1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results (e.g., from 8.0% to 7.0%) reduces the risk of microvascular complications (eye, kidney, and nerve diseases) by 40%.

Blood pressure control
Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with
diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by
approximately 33%.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to
diabetes is reduced by 12%.
Control of blood lipids
Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce
cardiovascular complications by 20% to 50%.

Blood pressure control

Blood pressure control reduces the risk of cardiovascular disease (heart disease or stroke) among persons with diabetes by 33% to 50%, and the risk of microvascular complications (eye, kidney, and nerve diseases) by approximately 33%. In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to diabetes is reduced by 12%.

Control of blood lipids

Improved control of cholesterol or blood lipids (for example, HDL, LDL, and triglycerides) can reduce cardiovascular complications by 20% to 50%.

Preventive care practices for eyes, kidneys, and feet

Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss by an estimated 50% to 60%. Comprehensive foot care programs can reduce amputation rates by 45% to 85%. Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in kidney function by 30% to 70%. Treatment with ACE inhibitors and angiotensin receptor blockers (ARBs) are more effective in reducing the decline in kidney function than other blood pressure lowering drugs.

Estimated diabetes costs in the United States in 2002

Total (direct and indirect): $132 billion -  Direct medical costs: $92 billion - Indirect costs: $40 billion (disability, work loss, premature mortality

 

 

Australia

 Diabetes Australia; Diabetes Australia - ACT; Diabetes Australia - Queensland

Diabetes Australia - NSW; Diabetes Australia - NT; Diabetes Australia - Victoria

Diabetes Australia - WA; Diabetes Australia - SA

 

United States

American Diabetes Association - their mission is to prevent and cure diabetes and improve the lives of those suffering with diabetes.

Diabetes Associations - An International Directory - an international directory of diabetes associations.

National Diabetes Information Clearinghouse - provides education material on diabetes

 

Canada

The Canadian Diabetes Association - to promote the health of Canadians through diabetes research, education, service and advocacy.

 

United Kingdom

Diabetes United Kingdom Home page - the United Kingdom charity for people with diabetes.

 

Other

International Diabetes Foundation (IDF) - The IDF takes a world view approach to diabetes. Its mission is to bring together people concerned with diabetes from throughout the world.

Joslin Diabetes Center - The Joslin Center provides medical treatment for people with diabetes and conducts research. Materials available to patients include books, videotapes and a quarterly newsletter.

Juvenile Diabetes Foundation International -This organization supports research to find a cure for diabetes. It publishes a quarterly journal and a series of patient education brochures about diabetes.

National Diabetes Information Clearinghouse - provides education material on diabetes

 

 

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